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The pivotal trials are STEP (semaglutide for weight management, The New England Journal of Medicine , 2021), SURMOUNT (tirzepatide for weight management, NEJM 2022), and SURMOUNT-OSA (tirzepatide for obstructive sleep apnea, NEJM 2024)

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Limit Acidic Foods and Drinks : Since omeprazole reduces stomach acid, eating highly acidic foods like citrus fruits, tomatoes, and coffee can irritate the stomach

these pro-inflammatory signaling pathways lead to proliferation and atherogenic transformation of VSMC [133]

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Qureshi GA, Qureshi AA, Devrajani BR, Chippa MA, Syed SA